TO BE FED UP WITH

Tá de saco cheio de alguém ou alguma coisa? 

Então, você está "Fed up with somenone/something".

Eg:

"I'm fed up with this noise upstairs! Those neighbors are a pain in the neck. I've had it!"
"He's fed up with her complaints. She criticizes every little thing she sees. Why can't she just enjoy the trip?"

What are you fed up with?